Fiorentina stunned the hosts by taking a third minute lead through Christian Kouame before Lautaro Martinez equalised on the stroke of halftime.
Inter, runners-up last season and seen as the main challengers to the dominance of champions Juventus this term, went ahead with a Federico Ceccherini own goal seven minutes after the break.
In a see-saw second half, Gaetano Castrovilli and Federico Chiesa scored twice in a six-minute spell to put Fiore 3-2 ahead, only for Romelu Lukaku to equalise in the 87th and Danilo D’Ambrosio to grab the winner two minutes later.
Source: wires
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